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Salem F, Barter ZE, Johnson TN & Rostami-Hodjegan A
Nov 2008
Theoretical assessment of metabolic drug interactions in paediatric population: the impact of age related fractional metabolism (fm) and its disparity between adults and neonates.
PKUK Meeting
November 26th-28th 2008, London Stanstead, UK.
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Rowland-Yeo K, Jamei M, Yang J, Tucker GT & Rostami-Hodjegan A
Oct 2008
Prediction of time-dependent CYP3A4-mediated in vivo drug-drug interactions from in vitro data using biological information on enzyme turnover implemented within a physiologically based model.
15th North American ISSX Meeting.
October 12th-16th 2008, San Diego, California.
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Johnson TN, Boussery K, Tucker GT & Rostami-Hodjegan A
May 2008
Prediction of the increased exposure to drugs in liver cirrhosis: a systems biology approach integrating prior information on disease with in vitro data on drug disposition.
10th European ISSX Meeting.
May 18th–21st 2008, Vienna, Austria.
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Polak S, Jamei M, Turner DB, Yang J, Neuhoff S, Tucker GT & Rostami-Hodjegan A
May 2008
Prediction of the in vivo behaviour of modified release formulations of metoprolol from in vitro dissolution profiles using the ADAM model (Simcyp V8).
10th European ISSX Meeting.
May 18th–21st 2008, Vienna, Austria.
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Neuhoff S, Yang J, Jamei M, Tucker GT & Rostami-Hodjegan A
May 2008
Simulation of the effect of P-glycoprotein on drug absorption in the human gastrointestinal tract.
10th European ISSX Meeting.
May 18th -21st 2008, Vienna, Austria.
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Neuhoff S, Barter ZE, Rowland-Yeo K, Tucker GT & Rostami-Hodjegan A
May 2008
In vitro-in vivo extrapolation of the clearance of drugs by glucuronidation: scaling factors for recombinant UGT1A1 data.
10th European ISSX Meeting.
May 18th -21st 2008, Vienna, Austria.
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Yang J, Liao M, Shou M, Jamei M, Rowland-Yeo K, Tucker GT & Rostami-Hodjegan A
May 2008
Cytochrome P450 turnover: methods for determining rates and implications for the prediction of drug interactions.
2nd Asian Pacific ISSX Meeting.
May 11th-13th 2008, Shanghai, China.
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Crewe HK, Barter ZE, Rowland-Yeo K, Tucker GT & Rostami-Hodjegan A
May 2008
Comparison of the catalytic activity per unit enzyme of recombinantly expressed and human liver microsomal cytochrome P450 2C9: determination of inter system extrapolation factors
10th European ISSX Meeting.
May 18th–21st 2008, Vienna, Austria.
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Perrett HF, Barter ZE, Lennard MS, Tucker GT & Rostami-Hodjegan A
May 2008
What is the level of expression of CYP2D6 in human liver? Influence of different calibration standards of the estimation of CYP2D6 abundance.
10th European ISSX Meeting.
May 18th–21st 2008, Vienna, Austria.
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Johnson TN, Boussery K, Polak S, Tucker GT & Rostami-Hodjegan, A
Mar 2008
Mechanistic models of human pharmacokinetics to predict the effects of liver cirrhosis on the clearance of nine drugs.
American Conference on Pharmacometrics.
March 9th-12th 2008, Tucson, Arizona, USA.
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