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Please view our latest papers below:
Jul 2010
PBPK modelling of inter-individual variability in the pharmacokinetics of environmental chemicals. Toxicology In Press, June 2010.
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Jun 2010
Resurgence in the use of physiologically based pharmacokinetic models in pediatric clinical pharmacology: parallel shift in incorporating the knowledge of biological elements and increased applicability to drug development and clinical practice. Paediatric Research In Press, May 2010.
Feb 2010
A semi-mechanistic model to predict the effects of liver cirrhosis on drug clearance. Clinical Pharmacokinetics 49(3), 189-206, March 2010.
Jan 2010
Physiologically based mechanistic modelling to predict complex drug–drug interactions involving simultaneous competitive and time-dependent enzyme inhibition by parent compound and its metabolite in both liver and gut - the effect of diltiazem on the time-course of exposure to triazolam. European Journal of Pharmaceutical Sciences 39(5), 298-309, March 2010.
