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Dec 2006
Prediction of plasma protein binding displacement and its implications for quantitative assessment of metabolic drug-drug interactions from in vitro data.
Journal of Pharmaceutical Sciences
95(12), 2778-2787, December 2006.
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Nov 2006
Prediction of clearance of eleven drugs and associated variability in neonates, infants and children.
Clinical Pharmacokinetics
45(9), 931-956, September 2006.
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Nov 2006
Implications of mechanism-based inhibition of CYP2D6 for the pharmacokinetics and toxicity of MDMA.
Journal of Psychopharmacology
20(6), 842-849, November 2006.
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Nov 2006
The impact of experimental design on assessing mechanism-based inactivation of CYP2D6 by MDMA (Ecstasy).
Journal of Psychopharmacology
20(6), 834-841, November 2006.
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Jul 2006
Prediction of metabolic drug clearance in humans: in vitro-in vivo extrapolation vs allometric scaling.
Xenobiotica
36(7), 567-580, July 2006.
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Jun 2006
Prediction of in vivo drug clearance from in vitro data.
I: Impact of inter-individual variability.
Xenobiotica
36(6), 473-497, June 2006.
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Jun 2006
Prediction of in vivo drug clearance from in vitro data.
II: Potential inter-ethnic differences.
Xenobiotica
36(6), 499-513, June 2006.
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Apr 2006
A critical evaluation of the experimental design of studies of mechanism based enzyme inhibition, with implications for in vitro-in vivo extrapolation.
Current Drug Metabolism
7(3), 315-334, April 2006.
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