home > products & services > workshops > konstanz, germany
Konstanz, Germany
Start Date: 11 Apr 2011
End Date: 15 Apr 2011
Intensive course:
‘Model-based drug development: Incorporating population variability into mechanistic prediction of PK and modelling of PK-PD’
Delegates will learn how to predict and assess:
- Metabolic drug clearance (CL)
- Metabolic drug-drug interactions (DDIs)
- Gut first-pass metabolism
- Oral drug absorption incorporating food effects and the impact of dosage form
- Effect of transporters and enterohepatic recirculation on kinetics and DDIs
- Drug distribution to different organs
- Population variability in drug concentration-time profiles
- Variation in kinetics in specific populations (paediatrics, ethnic groups, various disease populations)
- Pharmacodynamic effects of different compounds
- Time-course of drug in plasma that fits observed clinical data (achieved by combining fitting techniques with IVIVE, PBPK and drug specific in vitro data)
The workshops are split into two sessions and will be held at the Steigenberger Insel hotel in Konstanz. Delegates may register for all or part of the course:
Part I: 11th – 13th April 2011
Part II: 13th – 15th April 2011
Link to online booking form
Download Konstanz, April 2011, information (pdf)
For further details please contact Kelly Turton.
Simcyp Limited, Blades Enterprise Centre, John Street, Sheffield, S2 4SU UK
+44 (0) 114 2922321