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population based pharmacokinetic modelling and simulation

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Registrations now being taken for Simcyp workshops and seminar day in Tokyo, Japan

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Date: 21 Aug 2008

Simcyp welcomes registrations for the December 2008 workshops and seminar day in Tokyo, Japan. We recommend that delegates book now to secure a place and to take advantage of the early registration rates for this event.

Hands-on workshop on the 'Concepts of IVIVE'
8th - 9th December 2008

Seminar: 'Optimizing the use and interpretation of in vitro ADME studies'.
10th December 2008

Hands-on workshop on the 'Applications of IVIVE'
11th - 12th December 2008

The 'Concepts' and 'Applications' courses will follow a similar format to previous Simcyp workshops. Please click here for further information.

An impressive line-up of speakers has already been confirmed for the seminar day, which will be opened by Professor Yuichi Sugiyama. This will be an excellent opportunity for informal discussion with invited experts in the field. We welcome registrations from workshop attendees or from delegates who wish to attend the seminar day only.

Confirmed speakers include:

Professor Yuichi Sugiyama, University of Tokyo
‘Extrapolation and scaling of in vitro data to whole organ PBPK model: Application to drugs showing transporter-mediated distribution and clearance’

Professor Toshihisa Ishikawa, Tokyo Institute of Technology   
‘Pharmacogenomics and QSAR analysis of the human ABC transporter ABCG2’

Dr Sibylle Neuhoff, Simcyp Limited
‘Use or abuse of cell culture assays’

Professor Teruo Murakami,  Hiroshima International University
‘Involvement of efflux transporters in the intestinal absorption of various drugs’

Dr Ryusuke Takano, Chugai Pharmaceutical Co. Ltd
‘Oral absorption of poorly water-soluble drugs: Computer simulation of fraction absorbed’

Dr Karen Rowland-Yeo, Simcyp Limited
'Best use of in vitro data together with IVIVE to satisfy regulatory requirements for DDIs’

Professor Hiroshi Yamazaki, Showa Pharmaceutical University 
'Combining two new technologies: IVIVE meets microdosing’

Dr Shin-ichi Inoue, Daiichi-Sankyo
‘Risk assessment of DDI caused by metabolism-based CYP inhibition in the early stages of drug discovery’

Dr Hisakazu Ohtani, University of Tokyo
‘Making better use of in vitro information in tailoring individualised dose in clinical setting’

Professor Amin Rostami, University of Sheffield
‘Recognising covariates of PK: bottom-up vs top-down’

Please click here for details on how to register for this event. If you require any additional information please telephone Kelly Jinkinson at Simcyp on  +44 (0) 114 292 2321.


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